Descripción de la oferta
In our group we aim to generate highly selective and efficacious peptide and protein therapeutics by combining rational design, directed evolution, and bioinformatics. In this position, you will assist different projects involving the development of biotherapeutics. In the main project, you will contribute to developing peptide-based extracellular targeted protein degraders. In this position, you will apply phage display, next generation sequencing and bioinformatics to guide the selection of new degraders. You will participate in the production of the selected candidates using a peptide synthesizer and testing them in several rounds of optimization. You will also contribute to the development of proteins with activity on demand using protein modelling and to the generation of bioconjugates with the ability to cross the blood-brain barrier.
• Two years of funding with the possibility of an extension or transition into PhD position.
• Room for creativity, mentorship & team support.
• Proposed starting date: early 2025
Perfil buscado
• Requirement: master’s degree. Background in chemistry, biotechnology or related.
• Valuable experience: bioinformatics, protein production, chemical synthesis
• Strong motivation, proactivity, and creativity.
• Excellent teamwork abilities.
• Excellent communication skills and fluency in English.
Presentación de solicitudes
• Applications should be addressed to Dr. Benjamí Oller-Salvia (benjami.oller@iqs.url.edu) and Dr. Cristina Díaz (cristina.diaz@iqs.url.edu).
• Please include “RA PTher 2024 – Your Name” in the subject of your email.
• The following documents should be combined as a single pdf with your name:
o Motivation letter explaining why you would be a good fit for the position and our team.
o Curriculum Vitae
o Master’s and Bachelor’s academic records
o Contact details of two referees. Reference letters will be valued but not compulsory
