Descripción de la oferta
If you are passionate about metabolism, and translational biomedical research, and want to contribute to a project with strong clinical relevance, we warmly invite you to join
us at DIAMET and be part of CIRCASUC.
The Project
The CIRCASUC project aims to explore an innovative concept: the metabolite succinate as a key endogenous signal synchronizing circadian rhythms with metabolism via its
receptor SUCNR1. Our recent discoveries indicate that the succinate/SUCNR1 axis regulates core clock genes in adipose tissue and impacts crucial hormonal pathways (e.g.
insulin, leptin). By integrating animal models, in vitro systems, microbiota research, and human clinical cohorts, this project will elucidate how succinate acts as a molecular
bridge between clocks and metabolism, and how its dysregulation contributes to obesity and type 2 diabetes.
This is a unique opportunity to conduct a translational PhD at the intersection of chronobiology, metabolism, and biomedical innovation
The selected candidate will perform the following tasks:
• Conduct molecular, cellular, and animal-based experiments to investigate the succinate/SUCNR1 axis and its role in circadian and metabolic regulation.
• Perform metabolic, transcriptomic, and bioinformatic analyses of samples derived from in vitro models, animal models, and human cohorts.
• Manage and analyze experimental data, prepare reports, and contribute to scientific publications.
• Collaborate with team members across different disciplines (molecular biology, chronobiology, metabolism, clinical research).
• Actively participate in group meetings, scientific discussions, and presentations at national and international conferences.
Perfil buscado
We are seeking a highly motivated young scientist with a passion for biomedical research and an eagerness to tackle interdisciplinary challenges.
The candidate must have:
• BSc and MSc degree in Biology, Biochemistry, Biotechnology, Biomedical Sciences, or related fields.
• Strong academic record (≥ 8/10).
• Proficiency in English (oral and written).
• Holding an Animal Experimentation Certificate, or having completed the required course covering the functions a (caring), b (euthanasia), c(procedures), and d (project design) according to RD 53/2013, and currently performing the required practical training for the official accreditation of functions b and c.
• Eligibility to enroll in a PhD program in Spain.
IT WILL BE VALUED
• Experience in molecular and cellular biology techniques.
• Familiarity with cell culture and/or animal experimentation.
• Knowledge of bioinformatics or omics data analysis.
• Teamwork skills and strong scientific curiosity.
• Scientific and technical contributions. These include academic records and other curricular merits, as well as their suitability for the tasks to be performed based on
training and professional experience.
• The relevance and impact on the candidate’s research career of their stays at national or international centres.
• The suitability of the candidate for the research activities to be carried out. To this end, the added value that the project will bring to their research career will be taken
into account, as well as the value contributed to the centre and the group.
Presentación de solicitudes
The CV must include the DNI/NIE number or another personal identity document number and the academic records
• Send the CV, Motivation Letter and Contact details of at least 2 referees through the form that you will find on the bottom of the offer page https://www.iispv.cat/treballa-amb-nosaltres/
For any questions or queries: recruitment@iispv.cat
